TB-500

Overview

TB-500 is a synthetic peptide modeled on the active region of Thymosin Beta-4, a naturally occurring protein involved in actin regulation — the cytoskeletal protein that underlies cell movement and structural remodeling. Research interest in TB-500 centers on this actin-binding activity, which has made it a frequent subject of literature examining cell migration, tissue remodeling, and wound-healing models.

Genesis Genetics supplies TB-500 exclusively for laboratory and research applications. It is not sold, marketed, or intended for human or veterinary use.

Research Context

TB-500 is most often discussed in research contexts involving cell migration during tissue repair, angiogenesis, and recovery from induced tissue injury in animal models. Because Thymosin Beta-4 is expressed broadly across tissue types, much of the published interest spans multiple organ systems rather than a single mechanism. TB-500 is frequently studied alongside BPC-157 in recovery-focused research, despite acting through a distinct actin-regulation pathway rather than the angiogenic pathway associated with BPC-157.

Purity & Analytical Testing

Every TB-500 lot is verified by HPLC for identity and purity before release, documented on the included lot-specific Certificate of Analysis.

For more on how this testing fits into our broader release process, see Quality Control. For what the Certificate of Analysis itself contains, see Certificate of Analysis.

Storage & Handling

Lyophilized TB-500 should be stored refrigerated or frozen and protected from light prior to reconstitution; once reconstituted, keep refrigerated and use within a limited stability window.

For a full walkthrough of reconstitution technique and stability windows, see our research article on Peptide Storage 101. Bacteriostatic water for reconstitution is available on our Bac Water product page, and shipping/cold-chain handling for temperature sensitive orders is covered on our Shipping & Cold Chain page.

Related Compounds

TB-500 is frequently researched alongside compounds studied for adjacent or complementary research contexts, including ARA-290, BPC-157, Bac Water, MOTS-c, and NAD+. See the curated "Recommended With" section above for the full set.

Frequently Asked Questions